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Our patient presented with sudden onset of scrotal
2018-11-06
Our patient presented with sudden onset of scrotal enlargement and irritability. Although these symptoms were not usual manifestations of testicular torsion, they were compatible with those of a 3-month-old, since young infants may show obscure clinical features. A cystic testicular lesion is often
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Introduction Considering the importance of food safety
2018-11-06
Introduction Considering the importance of food safety and quality, more attention is being paid to the health of consumers [1]. However, due to nutrients deficiencies in human societies especially in certain periods of life, embracing, importing, and consumption of fortified foods is increasing [2
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br Materials and methods br Results br
2018-11-06
Materials and methods Results Discussion The present study clearly demonstrates anti-oxidant potential of A. calamus extracts as shown by inhibition of generation of free radicals, protection of DNA and mitochondria from oxidative damage as revealed by different in vitro assays and preventi
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Numerous researchers have pointed out
2018-11-06
Numerous researchers have pointed out that RC and its extracts possess functional properties from where advantages can be taken for developing new products with additional nutritious characteristics that may provide health benefits to consumers. In this cetrimonium bromide sense, one of the main cha
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Research into embryogenesis and nervous system development h
2018-11-06
Research into embryogenesis and nervous system development has been instrumental to the identification of factors required for cell specification. Using information gleaned from these studies, many groups have developed induction protocols to instruct hESCs and iPSCs to become a variety of neural ce
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Of the small number of genes whose transcription
2018-11-06
Of the small number of genes whose transcription differed by ≥3-fold between the two treatment groups (39, 51, and 93 out of 48,701 probe sets for E+G−, E+G+, and E−G+ fractions) (Figure 3G), most were upregulated in the WNT3A/BMP4-treated EBs (37, 43, and 61 probe sets, respectively). In the GFP+ f
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An important concern regarding stem cell
2018-11-06
An important concern regarding stem cell based therapies is the potential for unwanted cell growth. In a previous study we showed that the TheraCyte encapsulation device is durable enough to withstand freezing without evidence of cell escape, suggesting that once glycine transporter are sealed in d
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Using this approach we showed that the ReNcell VM
2018-11-06
Using this approach we showed that the ReNcell VM cell line can be cultivated in 3D microarray alginate spots, and preserve its proliferative progenitor state during on-chip expansion, albeit with lower proliferation rates and viabilities than those observed in conventional 2D culture platforms. Add
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While M macrophages may be the principal drivers of angiogen
2018-11-06
While M2 macrophages may be the principal drivers of angiogenesis associated with injury resolution, M1 macrophages are highly fibrolytic, which may facilitate angiogenesis, and secrete pro-angiogenic factors such as TNFα and IL-1β, and nitric oxide (Sunderkotter et al., 1994; Cooke & Losordo, 2002)
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The use of MaSCs from GFP mice
2018-11-06
The use of MaSCs from GFP mice for in vivo transplant into wild type recipients enabled us to examine the purity of FACS-gated basal and luminal cell populations from the regenerated GFP glands. All epithelial ap-1 transcription factor (GFP positive) were converged in the CD24+ population, while th
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In the present study we examined the above mentioned
2018-11-06
In the present study, we examined the above-mentioned properties of MSC-derived exosomes to limit cell death after myocardial I/R injury in vivo. We show that intact exosomes directly target cardiac procyanidin b2 to reduce infarct size. Furthermore, we demonstrate that, in line with our in vitro d
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br Resource table Resource details Episomal plasmids harbori
2018-11-06
Resource table. Resource details Episomal plasmids harboring the transgenes OCT4, SOX2, NANOG, LIN28, SV40LT, KLF4 and c-MYC were introduced into human mesenchymal stromal cyclohexamide derived from the fetal femur of the age 55days post-conception (fetal hMSCs) by nucleofection. In addition, a
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Recent publications provide inconsistent results whether
2018-11-06
Recent publications provide inconsistent results whether the overexpression of KLF4 is consistently accompanied with a more favorable outcome in all gastrointestinal cancer types. In HCC the order Saracatinib pattern of KLF4 is significantly increased compared to corresponding adjacent non-tumor sa
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In addition to supplying a source of growth factors
2018-11-06
In addition to supplying a source of growth factors and signaling molecules, blood vessels also provide a physical framework that can support the migration of neural progenitors during development and in the adult hygromycin b (Whitman et al., 2009). In the embryonic and adult rodent SVZ, newly bor
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The transgenic iPSCs differentiate into embryoid bodies
2018-11-06
The transgenic iPSCs differentiate into embryoid bodies (EBs) containing spontaneously beating EGFP-positive areas, which first appear on day 7–9 of differentiation (Fig. 2A). After 7days of puromycin treatment, nearly all non-cardiomyocytes in EBs are eliminated and the resistant purchase ABT-888
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