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To confirm the presence of gyrA or gyrA
2018-10-30
To confirm the presence of gyrA83 or gyrA87 mutations in qPCRgyrALp-positive samples, we tried to PCR-amplify and sequence a 383-bp fragment of the L. pneumophila gyrA QRDR directly from eight respiratory samples of patients #1 to #4 (Table 1). Using next-generation deep sequencing (NGS) technology,
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According to the Inverse Care Law
2018-10-30
According to the Inverse Care Law, the availability of medical care tends to vary inversely with the need for it in the lipid metabolism served (Hart, 1971). Other studies of multimorbid older adults have supported the existence of this health care utilization gradient, (Alter et al., 1999; Wang et
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br Hedgehog Pathway Inhibition Hedgehog Hh is a highly
2018-10-30
Hedgehog Pathway Inhibition Hedgehog (Hh) is a highly conserved signaling pathway, components of which include cell surface receptor Patched-1 (PTCH1), transmembrane receptor Smoothened (SMO), and three glioma associated family transcription factors (GLI) (Khan et al., 2015). It is involved with
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br Conflict of interest statements br Authors
2018-10-30
Conflict of interest statements Authors\' contributions Ethics committee approval Acknowledgments We would like to thank J. Visscher (Amsterdam Rheumatology and Immunology Center Department of Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam
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scopolamine hydrobromide br Conclusions and Future Questions
2018-10-29
Conclusions and Future Questions In this review, we have summarized current knowledge on biological age predictors and discussed different data types used. There are several existing predictors, where the most plausible candidates are the epigenetic clock and telomere length. They have both been
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br Acknowledgment Author would like to acknowledge the BK
2018-10-29
Acknowledgment Author would like to acknowledge the BK 21, Government of Korea (Republic of) for their funding to pursue this research program. Specifications table Value of the data Data, materials and methods Three types of data are presented in this data article and are available in
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We have previously demonstrated that
2018-10-29
We have previously demonstrated that relative levels of mitochondrial MIC26 and levels of secreted MIC26 can vary depending on the cell line investigated [1]. Here we show data deciphering whether depletion of MIC26 or MIC27 induces alterations in secreted levels of MIC26. Fig. 1B shows MIC26 deplet
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HIV co receptor tropism was assessed from the
2018-10-29
HIV-1 co-receptor AUY-922 was assessed from the filtered V3 MPS data using the g2p [454] tool and classified as X4 when there were more than 2% of the sequences with g2p false positivity rate (FPR) cutoffs of 3.75%, 2.5% and 1%. More detailed analysis was performed at FPR set at 2.5% to increase the
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br Experimental design materials and methods br Acknowledgem
2018-10-29
Experimental design, materials and methods Acknowledgements This research was supported by the Knut & Alice Wallenberg Foundation via the Wallenberg Wood Science Center, the Swedish Research Council Formas via CarboMat, and the European Research Council through Grant 336355 (“MicroDE”). The au
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In our case we use
2018-10-29
In our case we use =12 and also =26. MACD Moving Average Convergence/Divergence (MACD) is an oscillator that should reveal changes in the strength, direction, momentum, and duration of a trend in a stock׳s price. The simplest version of MACD is the difference between two moving averages, one ove
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br Acknowledgments We thank Marshall Burke Dimitri
2018-10-29
Acknowledgments We thank Marshall Burke, Dimitri Gershenson, seminar participants at Toulouse School of Economics, the Centre for the Study of African Economies at Oxford University, and two anonymous referees for useful comments. This research was made possible with the support and cooperation o
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px12 Similarly we were surprised that the amygdala did
2018-10-29
Similarly, we were surprised that the amygdala did not emerge in the age-related iFC analyses as a region of interest. VS activity would be modulated by the amygdala, itself under the control of cortical inputs (Ernst and Fudge, 2009). This finding may be particularly important for emotion regulatio
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However an accumulation of evidence
2018-10-29
However, an accumulation of evidence later indicated that vulnerable individuals identified in diathesis–stress models might instead be viewed as sensitive, developmentally plastic, and malleable vis-à-vis environmental influences, regardless of their valence. This alternate perspective led to the b
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In conclusion a novel feature
2018-10-29
In conclusion, a novel feature of the current study is the use of multi-method techniques, including daily diaries across 14days as well as dyadic retinoid x receptor scans. Our daily diary method to monitor how sleep-time changes day-by-day captures real life experience as it is lived (Bolger et a
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A brief review of the state
2018-10-29
A brief review of the state of analytical and empirical modeling was included in Anderson and Riegel [4]. In brief, the discussion stated that Tate [10], and independently Alekseevskii [11], modified the Bernoulli equation to account for projectile strength and target resistance. It further noted th
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