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In this study Rb increased the
2024-07-16
In this study, Rb1 increased the phosphorylation of p38 MAPK and Akt and macrophage phagocytosis of bacteria in mouse lung cells, consistent with the in vitro results. A recent study showed that Rb1 diminished the severity of lung injury in rats exposed to LPS. Rb1 inhibited the LPS-induced increase
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AdipoR and AdipoR have been reported to be
2024-07-16
AdipoR1 and AdipoR2 have been reported to be present in almost all type of tissues and low cl 2 levels have been observed in white adipose tissue (Inukai et al., 2005). These receptors have been observed to become deregulated with the onset of obesity, resulting in a reduced level of APN expression
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Though we have proved that VA could suppress hepatic
2024-07-16
Though, we have proved that VA could suppress hepatic gluconeogenesis, the mechanisms of VA on gluconeogenesis in vivo and in vitro remain unclear. AMP-activated protein kinase (AMPK), which is called an energy receptor enzyme, is widely expressed in liver and other tissues [23]. AMPK has become ano
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br Experimental section br Conflicts of interest
2024-07-16
Experimental section Conflicts of interest Acknowledgments This work was partly supported by INSA-Rouen, Rouen University, CNRS, Labex SynOrg (ANR-11-LABX-0029), Région Haute-Normandie. Introduction A key component of the integrated management of key pests such as codling moth (Cydia po
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br Acknowledgements DHA was funded by a research grant
2024-07-16
Acknowledgements DHA was funded by a research grant from Viamet and IMB and DHA were/are consultants for Viamet/Innocrin. DHA also supported by NIH P51-OD011106. Introduction Congenital adrenal hyperplasia resulting from 17alpha-hydroxylase and 17,20-lyase deficiency (17OHD) is a rare autosom
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We also measured macrophage infiltration and CLS presence
2024-07-16
We also measured macrophage infiltration and CLS presence in peri-gonadal AT from db/db mice and controls. CLS are morphological features within AT that are accurate indicators of adipocyte death and macrophage infiltration [56]. An earlier study showed that CLS macrophages account for >90% of the t
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It was deduced empirically that the helix direction of the
2024-07-16
It was deduced empirically that the helix direction of the COOC torsion might relate to the sign of the peroxide Cotton effect. Huang reported ab initio calculation of the peroxide bond using MRDCI method and DZP basis set, but only the fragment CH3OOCH3 instead of full molecule was studied [19]. Si
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JQ1 br Author Contributions br Acknowledgments br Introducti
2024-07-15
Author Contributions Acknowledgments Introduction Cerebral ischemia-reperfusion (I/R) injury is a pathological phenomenon that occurs after restoration of blood supply to JQ1 tissues subsequent to ischemia or hypoxia (Carden and Granger, 2000). It typically occurs after therapeutic thrombol
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It is noteworthy to mention the limitations of this study
2024-07-15
It is noteworthy to mention the limitations of this study like tPA plus LB1 treatment beyond 4 h after stroke was not investigated. Especially 6 or 8 h after stroke could be studied in future projects for translational purposes. Second drawback might be that we performed the experiments in different
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These results validate the docked pose of
2024-07-15
These results validate the docked pose of the ALR2-3e complex in comparison to the docked complex of the ALR2-4c complex of which the compound docked completely out of the binding pocket of ALR2 (). This concludes to that the removal of the acetic Ch 55 moiety leads to inactive or weakly active targ
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br Experimental br Acknowledgment br Introduction
2024-07-15
Experimental Acknowledgment Introduction The NADPH-dependent reduction of d-glucose catalyzed by aldose reductase (E.C.1.1.1.21) (AR) is considered as one of the phenomena leading to the onset of long term diabetic complications [as review see: [1], [2]. In fact, the reduction of the sugar,
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However there are a lot of external magnetic field disturban
2024-07-15
However, there are a lot of external magnetic field disturbances in urban environments, for example when the AHRS is close to a ferrous or magnetic object, which will disturb the output of magnetometer, then the observational errors cannot satisfy the assumption of Kalman filtering, and so, the atti
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Circulating adrenal derived stress hormones epinephrine and
2024-07-15
Circulating adrenal-derived stress hormones, epinephrine and corticosterone mediate their tissue effects through adrenergic (AR; α and β) and glucocorticoid (GR) receptors. AR are widely distributed throughout the body and although epinephrine is a prototypical agonist for all types of AR, the selec
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L-365,260 br Methods br Results br Discussion Adiponectin is
2024-07-15
Methods Results Discussion Adiponectin is naturally expressed and secreted exclusively from adipocytes, and adiponectin levels and its isoforms in circulation have recently been reported to highly associate with human coronary artery disease (CAD) [46], [47], [48], [49], these studies clear
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br Conflict s of interest
2024-07-15
Conflict(s) of interest Retinopathy of prematurity (ROP) is a leading cause of childhood blindness Retinopathy of prematurity (ROP) is a disease of premature infants which disrupts normal retinal vascularization (Fleck and McIntosh, 2008). With increased survival of extremely premature infants
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