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          br User knowledge representation Various representation appr2021-05-08  User knowledge representation Various representation approaches of user interests and preferences are proposed. In this work, we advocate a multidimensional semantic approach based on Bouzghoub et al. meta-model (Bouzeghoub and Kostadinov, 2005), depicted in Fig. 6, to model the user profile. The 
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          To our knowledge immunohistochemical analysis for proGRP was2021-05-08  To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor Bax channel blocker were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated se 
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          br Methods br Results br Discussion There are2021-05-08  Methods Results Discussion There are two particularly important facets of the present ERK findings relevant to drug conditioning. One is the strong ERK signal observed in the medial prefrontal cortex and the nucleus accumbens during the immediate post-trial interval following the final cond 
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          br Materials and methods br Results br Discussion2021-05-08  Materials and methods Results Discussion Here we show expression of the EP1 receptor in the hippocampus of mice and the functional influence of the EP1 receptor on kainic Ivacaftor induced seizures. Mice lacking a functional EP1 receptor gene displayed a lower tendency to enter status epile 
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          Nimodipine According to the Nomenclature Committee of the In2021-05-08  According to the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB, 1992), peptidases are divided into two classes, namely exopeptidases and endopeptidases, based on their actions on substrates and their active sites, respectively. Endopeptidases inclu 
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          3463 Expression of EBI and its function for2021-05-08  Expression of EBI2 and its function for migration in vitro in T cells was recently reported (Chalmin et al., 2015, Hannedouche et al., 2011, Liu et al., 2011, Pereira et al., 2009). Pereira et al. (2009) used an EBI2 reporter mouse and found that most CD4+ T cells, but only approximately half of the 
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          br Results br Discussion Previous studies2021-05-08  Results Discussion Previous studies have mapped ABCF1 as a risk factor gene for rheumatoid arthritis and autoimmune pancreatitis (Ota et al., 2007, Richard et al., 1998). Additionally, recent genome-wide association studies have also associated ABCF1 with the risk of gout (Dong et al., 2017) a 
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          In conclusion our results demonstrate that2021-05-08  In conclusion, our results demonstrate that CCLP promoted osteoblast proliferation, differentiation, and mineralization via activation of ERK, p38, and Smad1/5/8 (Fig. 9). The residues of the GGKQNVGFGP-sequence in CCLP showed the highest significant binding relationship with the target activin rece 
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          E protein expressed in a2021-05-08  E1 protein expressed in a plasmid encoding codon-optimized canine oral papillomavirus (COPV) led to therapeutic immunization of COPV-infected Beagle dogs [25], [26], which was better than that achieved with plasmids encoding E2 or E7 COPV. Moreover, E1 and E2 from cottontail rabbit papillomavirus ( 
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          br Materials and Methods br Acknowledgements2021-05-08  Materials and Methods Acknowledgements We thank the staff of beamlines ID29 and ID30A-1 of the European Synchrotron Radiation Facility. This work was supported by, the Marie Curie Career Integration Grant (PCIG13-GA-2013-630755), the Israel Science Foundation (Grant 1383/17) and the Israeli Ca 
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          Presumably LBPs have health promoting activities such as2021-05-08  Presumably, LBPs have health-promoting activities, such as antioxidant, immune regulation, anti-stress, anticancer, neuroprotective and antidiabetic activities [[7], [8], [9], [10], [11]]; LBPs can improve the whole-body health status of mice and stimulate the expressions of IL-2, IL-12 and TNF-α, w 
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          The protein levels of the three2021-05-08  The protein levels of the three enzymes in the organs in the three earthworm species ranked body wall > intestine > seminal receptacle ≈ seminal vesicle (Fig. 3B).The presence of significant detoxification capability in the body wall would be logically expected in a soil dwelling organism, to facili 
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          pterostilbene Bovine collagen type II a fibrillar collagen2021-05-07  Bovine collagen type II, a fibrillar collagen mainly found in cartilage, comprises 24 potentially glycosylated lysine residues within its collagen domain. Detailed analysis revealed that 22 out of 23 of these lysine residues are hydroxylated and carry variable numbers of Gal(β1-O) and Glc(α1-2)Gal(β 
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          The intestinal cholesterol absorption markers sitosterol and2021-05-07  The intestinal cholesterol IL-4, murine recombinant markers sitosterol and campesterol to cholesterol levels were significantly lower in Villin-Tgif1 mice compared to wild type mice, irrespective of diet. However, the decrease was less pronounced in Villin-Tgif1 mice fed a chow diet (∼20–30%) compa 
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          Data on optimal hormone formulations routes2021-05-07  Data on optimal hormone formulations, routes of administration, doses and duration of hormone use in young women with POF are lacking (Box 1). Transdermal pdgfr inhibitor administration, which avoids the first-pass hepatic circulation and the increase in inflammatory markers such as C-reactive prot 
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