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In a previous report it was speculated that withdrawal syndr
2019-06-12

In a previous report, it was speculated that withdrawal syndrome after IM cessation was related to a loss of blocking tyrosine kinases, such as c-kit and platelet-derived growth factor receptor (PDGFR) [2]. The inhibition of c-kit and PDGFR by IM reduces and increases the number of osteoclasts and o
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Chronic hepatitis B virus HBV infection is
2019-06-12

Chronic NMS-873 virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV continues to be a cha
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br Purpose br Methods Participating
2019-06-12

Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register
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Most spinal schwannomas derived from Schwann cells along the
2019-06-12

Most spinal schwannomas derived from Schwann rgd peptide along the dorsal sensory roots involve radicular pain as the most common initial symptom. However, symptoms may be subtle and progress slowly over time, owing to the slow-growing nature of these tumors. In our case, it\'s more difficult to thi
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br Conclusion br Conflict of interest br Introduction Dermat
2019-06-12

Conclusion Conflict of interest Introduction Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue neoplasm that was first identified by Taylor, RW in 1890. It was then described in 1924 by Darier, J and Ferrand, M as a progressive recurrent dermatofibroma, and was later termed DFSP
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Introduction Bone metastases are a common manifestation of
2019-06-12

Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and mst1 kinase of the spinal cord or cauda equina [2]. Many randomized studies have been conducted to
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Fulvestrant To date over mutations in KCNQ have been
2019-06-12

To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [
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The most compelling apparent evidence in support of the
2019-06-12

The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with B
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In Blake Alkire and colleagues
2019-06-12

In , Blake Alkire and colleagues now provide additional measures to help us gain political priority on the public health agendas. In this study, Alkire and colleagues modelled access to surgery in 180 countries on the basis of four criteria: timeliness, surgical capacity, safety, and affordability.
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In addition to being a key determinant of the risk
2019-06-12

In addition to being a key determinant of the risk of acquiring infection, nutritional status is a principal determinant of the health trajectory and outcomes following discharge from hospital. Among Gambian children admitted with pneumonia, even being moderately underweight was associated with a ra
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En realidad el texto con el que Granada concluye su
2019-06-12

En realidad el texto, con el que Granada concluye su Introducción al Símbolo de la Fé, consta de diez capítulos en los que se insiste en no explicar TCEP los que quieran convertirse de manera inmediata “los misterios del cristianismo, porque no creen aún, sino que hay que llevarlos por la vía de la
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Por otro lado el proceso
2019-06-12

Por otro lado, el proceso de negociaciones que llevan FH535 cabo ambos gobiernos, demuestra, según estudiosos estadounidenses, que hay un reconocimiento de parte de los funcionarios de Estados Unidos, de que Cuba está ayudando a poner fin a la insurgencia de las farc en Colombia, que pueden tener in
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Consequently in asymptomatic individuals multiple
2019-06-11

Consequently, in asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. Moreover, in addition recording at higher lead
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It is noted that in this study BrS
2019-06-11

It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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br Implementation of a programme called the the
2019-06-11

Implementation of a programme called the , the key component of the UNICEF/WHO Baby-Friendly Hospital Initiative (BFHI) increases exclusive breastfeeding at 3 months, any breastfeeding at 12 months, and reduces diarrhoeal disease. These outcomes were shown in a cluster-randomised study of 31 hospi
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