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Treatments against TNF exhibit a remarkable clinical respons
2018-11-05
Treatments against TNF-α exhibit a remarkable clinical response in some UC patients (Danese et al., 2013), but the majority of emerging selective ADAM17 inhibitors which target TNF-α shedding in human inflammatory diseases are not successful (Duffy et al., 2011). The information in the present study
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The Adipose Graft Transposition Procedure AGTP uses patient
2018-11-05
The Adipose Graft Transposition Procedure (AGTP) uses patient\'s existing cardiac fat directly, placing it over the myocardial infarcted zones, rather than explanting a cardiac adipose biopsy to retrieve the p-gp inhibitors list (Gálvez-Montón et al., 2011; Gálvez-Montón et al., 2013b). In the acut
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In pursuit of improving the identification and
2018-11-05
In pursuit of improving the identification and profiling of low-abundance peptides, we developed a streamlined, mass spectrometry-based platform for the characterization of low-abundance plk inhibitor in blood and in tissue. As illustrated in Fig. 1, the developed pipeline involves an isolation and
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br The recent meta analysis in by Shen and colleagues
2018-11-05
The recent meta-analysis in by Shen and colleagues is the first to report a systematic analysis of the diagnostic performance of bronchoalveolar lavage fluid (BALF) CD4/CD8 ratios in sarcoidosis (). Their results are consistent with numerous studies and BAL guidelines over the last 2 decades whic
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HLA transgenic mice are widely used to model
2018-11-05
HLA-transgenic mice are widely used to model the human T cell response in mice. We focused the present study on the HLA B*0702 allele, which is associated with strong T cell response in terms of magnitude and breath (Weiskopf et al., 2013), thereby allowing us to test the role of multiple cross-reac
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Consistent with our overall assertion
2018-11-05
Consistent with our overall assertion that serotype-specific, conserved, and cross-reactive T methysergide all can contribute to protection against DENV infection, phase 2b and 3 trials of Sanofi\'s DENV-yellow fever virus (YFV) chimeric vaccine showed limited efficacy depending on the serotype and
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br Materials and methods br Results and discussion br Conclu
2018-11-05
Materials and methods Results and discussion Conclusions According to reaction-based kinetic models, the best correlation was obtained for the pseudo-second order model which presented higher values of R2 (greater than 0.99) and confirm that the protein sorption kinetics of OPN extract have
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order RPC1063 Introduction The Sn and W mineral deposits in
2018-11-05
Introduction The Sn and W mineral deposits in southern China were historically suggested to have formed as part of one mineralizing event (Hsu, 1943), although the W ores are mainly distributed in the eastern part of southern China, whereas most Sn deposits are in the western part (Chen et al., 198
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Notably the sleeping environment in which home studies are c
2018-11-05
Notably, the sleeping environment in which home studies are conducted is often not standardized especially with respect to ambient temperatures due to seasonal changes. According to the data collected from Summer 2012 to Summer 2014 in Australian houses by the Faculty of Architecture, The University
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br Conclusion Key contributions of this study are the sugges
2018-11-05
Conclusion Key contributions of this study are the suggestion that one week of antibiotic treatment is insufficient to effect important changes in the gut ecosystem in most CFS participants, that reducing the levels of gram-positive gut microbiota is associated with some improvement in objective
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br Material and methods All studies were
2018-11-05
Material and methods All studies were performed at Emory University under an IACUC approved protocol (170-2003). Pregnant rats received dietary supplementation with ω-3 PUFAs by adding menhaden fish oil 15% weight by weight (w/w) (Sigma-Aldrich) into standard rat chow mix, to achieve a total dail
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Temperature rhythm is an important phase marker for
2018-11-05
Temperature rhythm is an important phase marker for chronobiological studies, however, the use of core body temperature rhythm in longitudinal researches has always been limited by restrictions for continuous use of data recording devices, such as rectal probes. Wrist temperature, recorded by a ther
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Because of the high impact
2018-11-05
Because of the high impact of biofouling on process operation and by implication high economic cost, in recent years there has been an increasing interest in developing an on – line sensor able to monitor biofilm formation in real time, especially in an early stage [7–9]. Despite all the efforts to
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br Materials and methods br
2018-11-03
Materials and methods Acknowledgments We thank the Institut National de Recherche en Sciences et Technologies pour l׳Environnement et l׳Agriculture (France), the Commissariat à l׳Energie Atomique et aux Energies Alternatives (France) through the Transversal Toxicology Program (Pptox), the Agen
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AP20187 cost br Data br Experimental design materials and me
2018-11-03
Data Experimental design, materials and methods Acknowledgements Data Silk fibroin is a natural fibrous protein with advantages for protein loading and delivery in vitro and vivo. However, presumably because of the super-negative charge of fibroin, the application of intracellular delive
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