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In terms of substance specific mechanisms of action nicotine
2018-11-07
In terms of substance-specific mechanisms of action, nicotine facilitates dopaminergic neurotransmission within cytochrome p450 inhibitors reward pathways via activating nicotinic actylcholine (nAch) receptors, including those located on nerve terminals in VTA projections to the NAcc (D\'souza and
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Findings are relevant to both intervention targets
2018-11-07
Findings are relevant to both intervention targets (e.g., personalized medicine) and intervention mechanisms. For example, an emerging literature suggests that targeted interventions remediating attentional vigilance (‘ABM’ procedures) have a broad impact on clinical anxiety symptoms (Hakamata et al
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br Materials and methods br
2018-11-07
Materials and methods Results Discussion We hypothesize that the relative weakness of the canonical response to the normal and the 60% compression rates is due to habituation to the stimuli across time. This habituation can be quite fast, and may happen already within the first block. While
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Underlying AI relevant aspects of organizational change
2018-11-06
Underlying AI relevant aspects of organizational change are important in the context of classroom instruction within a course or a program in architecture. Students are given the opportunity to organize themselves in teams, make selections of environments they see relevant to assess, collaborate eff
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French Jesuits published the handbook dated March preface in
2018-11-06
French Jesuits published the handbook, dated 19 March 1926 (preface), in this context of polarization between two schools, the old one and the new one, within the China mission. The handbook’s preface opens with a statement: “This brochure is not made for cathedral builders. This is not even an essa
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International Consultancy Firms in the domain of
2018-11-06
International Consultancy Firms in the domain of Urban Planning (ICFUP), which include architecture- and engineering-oriented firms, are the major agents in expanding the channels of cross-border policy transfer (Peck, 2003) and in transferring policies, practices, models, and references that can be
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The statue of the famous emperor Marcus Aurelius was in
2018-11-06
The statue of the famous emperor Marcus Aurelius was, in fact, the centerpiece of Michelangelo׳s piazza on the Capitolium. In 1538, Pope Paul III moved the statue here from S. Giovanni in Laterano (i.e., the basilica of S. John at the Lateran) where it stood for centuries and was miraculously preser
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Our patient presented with sudden onset of scrotal
2018-11-06
Our patient presented with sudden onset of scrotal enlargement and irritability. Although these symptoms were not usual manifestations of testicular torsion, they were compatible with those of a 3-month-old, since young infants may show obscure clinical features. A cystic testicular lesion is often
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Introduction Considering the importance of food safety
2018-11-06
Introduction Considering the importance of food safety and quality, more attention is being paid to the health of consumers [1]. However, due to nutrients deficiencies in human societies especially in certain periods of life, embracing, importing, and consumption of fortified foods is increasing [2
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br Materials and methods br Results br
2018-11-06
Materials and methods Results Discussion The present study clearly demonstrates anti-oxidant potential of A. calamus extracts as shown by inhibition of generation of free radicals, protection of DNA and mitochondria from oxidative damage as revealed by different in vitro assays and preventi
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Numerous researchers have pointed out
2018-11-06
Numerous researchers have pointed out that RC and its extracts possess functional properties from where advantages can be taken for developing new products with additional nutritious characteristics that may provide health benefits to consumers. In this cetrimonium bromide sense, one of the main cha
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Research into embryogenesis and nervous system development h
2018-11-06
Research into embryogenesis and nervous system development has been instrumental to the identification of factors required for cell specification. Using information gleaned from these studies, many groups have developed induction protocols to instruct hESCs and iPSCs to become a variety of neural ce
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Of the small number of genes whose transcription
2018-11-06
Of the small number of genes whose transcription differed by ≥3-fold between the two treatment groups (39, 51, and 93 out of 48,701 probe sets for E+G−, E+G+, and E−G+ fractions) (Figure 3G), most were upregulated in the WNT3A/BMP4-treated EBs (37, 43, and 61 probe sets, respectively). In the GFP+ f
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An important concern regarding stem cell
2018-11-06
An important concern regarding stem cell based therapies is the potential for unwanted cell growth. In a previous study we showed that the TheraCyte encapsulation device is durable enough to withstand freezing without evidence of cell escape, suggesting that once glycine transporter are sealed in d
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Using this approach we showed that the ReNcell VM
2018-11-06
Using this approach we showed that the ReNcell VM cell line can be cultivated in 3D microarray alginate spots, and preserve its proliferative progenitor state during on-chip expansion, albeit with lower proliferation rates and viabilities than those observed in conventional 2D culture platforms. Add
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